Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease

Exp. Biol. Med. 2007;232:323-335
© 2007 Society for Experimental Biology and Medicine

 

This Article
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease

Abstract

Full Text

Full Text (PDF)


Alert me when this article is cited

Alert me if a correction is posted
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease
Services
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease

Email this article to a friend

Similar articles in this journal


Alert me to new issues of the journal

Download to citation manager

Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease
Citing Articles
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease

Citing Articles via HighWire
Citing Articles via Google Scholar
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease
Google Scholar
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease

Articles by Brewer, G. J.
Search for Related Content
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease
Social Bookmarking
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease
Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease

What’s this?


George J. Brewer1


Department of Human Genetics, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan



View larger version (11K):
[in this window]
[in a new window]
Figure 1. This figure identifies the major risk factors leading to atherosclerosis, and suggest that production of ROS by excessive free iron and copper, oxidation of LDL by iron and copper, and interaction of iron and copper with homocysteine, fits into this scheme. ROS, reactive oxygen species; LDL, low-density lipoprotein.

Iron and Copper Toxicity in Diseases of Aging, Particularly Atherosclerosis and Alzheimer’s Disease
CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What’s this?